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Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling
Bone morphogenetic protein (BMP) pathways control an array of developmental and homeostatic events, and must themselves be exquisitely controlled. Here, we identify Caenorhabditis elegans SMA-10 as a positive extracellular regulator of BMP–like receptor signaling. SMA-10 acts genetically in a BMP–li...
Autores principales: | Gumienny, Tina L., MacNeil, Lesley, Zimmerman, Cole M., Wang, Huang, Chin, Lena, Wrana, Jeffrey L., Padgett, Richard W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873917/ https://www.ncbi.nlm.nih.gov/pubmed/20502686 http://dx.doi.org/10.1371/journal.pgen.1000963 |
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