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Neisseria meningitidis Opc Invasin Binds to the Sulphated Tyrosines of Activated Vitronectin to Attach to and Invade Human Brain Endothelial Cells

The host vasculature is believed to constitute the principal route of dissemination of Neisseria meningitidis (Nm) throughout the body, resulting in septicaemia and meningitis in susceptible humans. In vitro, the Nm outer membrane protein Opc can enhance cellular entry and exit, utilising serum fact...

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Detalles Bibliográficos
Autores principales: Sa E Cunha, Claudia, Griffiths, Natalie J., Virji, Mumtaz
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873925/
https://www.ncbi.nlm.nih.gov/pubmed/20502634
http://dx.doi.org/10.1371/journal.ppat.1000911