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Selection in spatial stochastic models of cancer: Migration as a key modulator of fitness
BACKGROUND: We study the selection dynamics in a heterogeneous spatial colony of cells. We use two spatial generalizations of the Moran process, which include cell divisions, death and migration. In the first model, migration is included explicitly as movement to a proximal location. In the second,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873940/ https://www.ncbi.nlm.nih.gov/pubmed/20406439 http://dx.doi.org/10.1186/1745-6150-5-21 |