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Eef1a2 Promotes Cell Growth, Inhibits Apoptosis and Activates JAK/STAT and AKT Signaling in Mouse Plasmacytomas

BACKGROUND: The canonical function of EEF1A2, normally expressed only in muscle, brain, and heart, is in translational elongation, but recent studies suggest a non-canonical function as a proto-oncogene that is overexpressed in a variety of solid tumors including breast and ovary. Transcriptional pr...

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Detalles Bibliográficos
Autores principales: Li, Zhaoyang, Qi, Chen-Feng, Shin, Dong-Mi, Zingone, Adriana, Newbery, Helen J., Kovalchuk, Alexander L., Abbott, Catherine M., Morse, Herbert C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873962/
https://www.ncbi.nlm.nih.gov/pubmed/20505761
http://dx.doi.org/10.1371/journal.pone.0010755