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Eef1a2 Promotes Cell Growth, Inhibits Apoptosis and Activates JAK/STAT and AKT Signaling in Mouse Plasmacytomas
BACKGROUND: The canonical function of EEF1A2, normally expressed only in muscle, brain, and heart, is in translational elongation, but recent studies suggest a non-canonical function as a proto-oncogene that is overexpressed in a variety of solid tumors including breast and ovary. Transcriptional pr...
Autores principales: | Li, Zhaoyang, Qi, Chen-Feng, Shin, Dong-Mi, Zingone, Adriana, Newbery, Helen J., Kovalchuk, Alexander L., Abbott, Catherine M., Morse, Herbert C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873962/ https://www.ncbi.nlm.nih.gov/pubmed/20505761 http://dx.doi.org/10.1371/journal.pone.0010755 |
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