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Deletion Mutants of VPg Reveal New Cytopathology Determinants in a Picornavirus

BACKGROUND: Success of a viral infection requires that each infected cell delivers a sufficient number of infectious particles to allow new rounds of infection. In picornaviruses, viral replication is initiated by the viral polymerase and a viral-coded protein, termed VPg, that primes RNA synthesis....

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Detalles Bibliográficos
Autores principales: Arias, Armando, Perales, Celia, Escarmís, Cristina, Domingo, Esteban
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873979/
https://www.ncbi.nlm.nih.gov/pubmed/20505767
http://dx.doi.org/10.1371/journal.pone.0010735