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Deletion Mutants of VPg Reveal New Cytopathology Determinants in a Picornavirus
BACKGROUND: Success of a viral infection requires that each infected cell delivers a sufficient number of infectious particles to allow new rounds of infection. In picornaviruses, viral replication is initiated by the viral polymerase and a viral-coded protein, termed VPg, that primes RNA synthesis....
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873979/ https://www.ncbi.nlm.nih.gov/pubmed/20505767 http://dx.doi.org/10.1371/journal.pone.0010735 |