Comparative Therapeutic Effects of Velaglucerase Alfa and Imiglucerase in a Gaucher Disease Mouse Model

Gaucher disease type 1 is caused by the defective activity of the lysosomal enzyme, acid β-glucosidase (GCase). Regular infusions of purified recombinant GCase are the standard of care for reversing hematologic, hepatic, splenic, and bony manifestations. Here, similar in vitro enzymatic properties,...

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Detalles Bibliográficos
Autores principales: Xu, You-Hai, Sun, Ying, Barnes, Sonya, Grabowski, Gregory A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873993/
https://www.ncbi.nlm.nih.gov/pubmed/20505772
http://dx.doi.org/10.1371/journal.pone.0010750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873993/
https://www.ncbi.nlm.nih.gov/pubmed/20505772
http://dx.doi.org/10.1371/journal.pone.0010750

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