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High-Throughput High-Resolution Class I HLA Genotyping in East Africa

HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria, and tuberculosis, but the HLA genetic diversi...

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Detalles Bibliográficos
Autores principales: Koehler, Rebecca N., Walsh, Anne M., Sanders-Buell, Eric E., Eller, Leigh Anne, Eller, Michael, Currier, Jeffrey R., Bautista, Christian T., Wabwire-Mangen, Fred, Hoelscher, Michael, Maboko, Leonard, Kim, Jerome, Michael, Nelson L., Robb, Merlin L., McCutchan, Francine E., Kijak, Gustavo H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873994/
https://www.ncbi.nlm.nih.gov/pubmed/20505773
http://dx.doi.org/10.1371/journal.pone.0010751