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A Novel SALL4/OCT4 Transcriptional Feedback Network for Pluripotency of Embryonic Stem Cells

BACKGROUND: SALL4 is a member of the SALL gene family that encodes a group of putative developmental transcription factors. Murine Sall4 plays a critical role in maintaining embryonic stem cell (ES cell) pluripotency and self-renewal. We have shown that Sall4 activates Oct4 and is a master regulator...

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Detalles Bibliográficos
Autores principales: Yang, Jianchang, Gao, Chong, Chai, Li, Ma, Yupo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874005/
https://www.ncbi.nlm.nih.gov/pubmed/20505821
http://dx.doi.org/10.1371/journal.pone.0010766