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Distinct Molecular Evolutionary Mechanisms Underlie the Functional Diversification of the Wnt and TGFβ Signaling Pathways

The canonical Wnt pathway is one of the oldest and most functionally diverse of animal intercellular signaling pathways. Though much is known about loss-of-function phenotypes for Wnt pathway components in several model organisms, the question of how this pathway achieved its current repertoire of f...

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Detalles Bibliográficos
Autores principales: Konikoff, Charlotte E., Wisotzkey, Robert G., Stinchfield, Michael J., Newfeld, Stuart J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874024/
https://www.ncbi.nlm.nih.gov/pubmed/20339843
http://dx.doi.org/10.1007/s00239-010-9337-z