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Tumor-associated macrophages in clear cell renal cell carcinoma express both gastrin-releasing peptide and its receptor: a possible modulatory role of immune effectors cells

PURPOSE: Renal cell carcinomas (RCC) frequently express the gastrin-releasing peptide receptor (GRP-R). Gastrin-releasing peptide (GRP) stimulates tumor cell proliferation and neoangiogenesis. Tumor-associated macrophages (TAM) comprise an important cellular component of these tumors. We analyzed th...

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Detalles Bibliográficos
Autores principales: Bedke, Jens, Hemmerlein, Bernhard, Perske, Christina, Gross, Andreas, Heuser, Markus
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874056/
https://www.ncbi.nlm.nih.gov/pubmed/20012906
http://dx.doi.org/10.1007/s00345-009-0492-z