3α-Androstanediol, but Not Testosterone, Attenuates Age-Related Decrements in Cognitive, Anxiety, and Depressive Behavior of Male Rats

Some hippocampally-influenced affective and/or cognitive processes decline with aging. The role of androgens in this process is of interest. Testosterone (T) is aromatized to estrogen, and reduced to dihydrotestosterone (DHT), which is converted to 5α-androstane, 3α, 17α-diol (3α-diol). To determine...

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Detalles Bibliográficos
Autores principales: Frye, Cheryl A., Edinger, Kassandra L., Lephart, Edwin D., Walf, Alicia A.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874398/
https://www.ncbi.nlm.nih.gov/pubmed/20552051
http://dx.doi.org/10.3389/fnagi.2010.00015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874398/
https://www.ncbi.nlm.nih.gov/pubmed/20552051
http://dx.doi.org/10.3389/fnagi.2010.00015

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