Disruption of a Quorum Sensing mechanism triggers tumorigenesis: a simple discrete model corroborated by experiments in mammary cancer stem cells

BACKGROUND: The balance between self-renewal and differentiation of stem cells is expected to be tightly controlled in order to maintain tissue homeostasis throughout life, also in the face of environmental hazards. Theory, predicting that homeostasis is maintained by a negative feedback on stem cel...

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Detalles Bibliográficos
Autores principales: Agur, Zvia, Kogan, Yuri, Levi, Liora, Harrison, Hannah, Lamb, Rebecca, Kirnasovsky, Oleg U, Clarke, Robert B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874533/
https://www.ncbi.nlm.nih.gov/pubmed/20406437
http://dx.doi.org/10.1186/1745-6150-5-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874533/
https://www.ncbi.nlm.nih.gov/pubmed/20406437
http://dx.doi.org/10.1186/1745-6150-5-20

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