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Genome-wide profiling of gene expression in the epididymis of alpha-chlorohydrin-induced infertile rats using an oligonucleotide microarray

BACKGROUND: As one of the chlorinated antifertility compounds, alpha-chlorohydrin (ACH) can inhibit glyceraldehyde-3-phosphate dehydrogenase (G3PDH) activity in epididymal sperm and affect sperm energy metabolism, maturation and fertilization, eventually leading to male infertility. Further studies...

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Detalles Bibliográficos
Autores principales: Xie, Shuwu, Zhu, Yan, Ma, Li, Lu, Yingying, Zhou, Jieyun, Gui, Youlun, Cao, Lin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874557/
https://www.ncbi.nlm.nih.gov/pubmed/20409345
http://dx.doi.org/10.1186/1477-7827-8-37