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Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo

OBJECTIVE: Insulin-mediated suppression of hepatic glucose production (HGP) is associated with sensitive intracellular signaling and molecular inhibition of gluconeogenic (GNG) enzyme mRNA expression. We determined, for the first time, the time course and relevance (to metabolic flux) of these molec...

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Detalles Bibliográficos
Autores principales: Ramnanan, Christopher J., Edgerton, Dale S., Rivera, Noelia, Irimia-Dominguez, Jose, Farmer, Ben, Neal, Doss W., Lautz, Margaret, Donahue, E. Patrick, Meyer, Catalina M., Roach, Peter J., Cherrington, Alan D.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874690/
https://www.ncbi.nlm.nih.gov/pubmed/20185816
http://dx.doi.org/10.2337/db09-1625