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Lipocalin-2 Deficiency Impairs Thermogenesis and Potentiates Diet-Induced Insulin Resistance in Mice

OBJECTIVE: Lipocalin (LCN) 2 belongs to the lipocalin subfamily of low–molecular mass–secreted proteins that bind small hydrophobic molecules. LCN2 has been recently characterized as an adipose-derived cytokine, and its expression is upregulated in adipose tissue in genetically obese rodents. The ob...

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Detalles Bibliográficos
Autores principales: Guo, Hong, Jin, Daozhong, Zhang, Yuanyuan, Wright, Wendy, Bazuine, Merlijn, Brockman, David A., Bernlohr, David A., Chen, Xiaoli
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874698/
https://www.ncbi.nlm.nih.gov/pubmed/20332347
http://dx.doi.org/10.2337/db09-1735