Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism

OBJECTIVE: Rictor is an essential component of mammalian target of rapamycin (mTOR) complex (mTORC) 2, a kinase that phosphorylates and activates Akt, an insulin signaling intermediary that regulates glucose and lipid metabolism in adipose tissue, skeletal muscle, and liver. To determine the physiol...

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Detalles Bibliográficos
Autores principales: Kumar, Anil, Lawrence, John C., Jung, Dae Young, Ko, Hwi Jin, Keller, Susanna R., Kim, Jason K., Magnuson, Mark A., Harris, Thurl E.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874700/
https://www.ncbi.nlm.nih.gov/pubmed/20332342
http://dx.doi.org/10.2337/db09-1061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874700/
https://www.ncbi.nlm.nih.gov/pubmed/20332342
http://dx.doi.org/10.2337/db09-1061

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