Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Overexpression Increases Lipid Oxidation in Myocytes From Extremely Obese Individuals

OBJECTIVE: To determine whether the obesity-related decrement in fatty acid oxidation (FAO) in primary human skeletal muscle cells (HSkMC) is linked with lower mitochondrial content and whether this deficit could be corrected via overexpression of peroxisome proliferator–activated receptor-γ coactiv...

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Detalles Bibliográficos
Autores principales: Consitt, Leslie A., Bell, Jill A., Koves, Timothy R., Muoio, Deborah M., Hulver, Matthew W., Haynie, Kimberly R., Dohm, G. Lynis, Houmard, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874701/
https://www.ncbi.nlm.nih.gov/pubmed/20200320
http://dx.doi.org/10.2337/db09-1704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874701/
https://www.ncbi.nlm.nih.gov/pubmed/20200320
http://dx.doi.org/10.2337/db09-1704

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