Ectopic Expression of E2F1 Stimulates β-Cell Proliferation and Function

OBJECTIVE: Generating functional β-cells by inducing their proliferation may provide new perspectives for cell therapy in diabetes. Transcription factor E2F1 controls G(1)- to S-phase transition during the cycling of many cell types and is required for pancreatic β-cell growth and function. However,...

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Detalles Bibliográficos
Autores principales: Grouwels, Gael, Cai, Ying, Hoebeke, Inge, Leuckx, Gunter, Heremans, Yves, Ziebold, Ulrike, Stangé, Geert, Chintinne, Marie, Ling, Zhidong, Pipeleers, Daniel, Heimberg, Harry, Van de Casteele, Mark
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874704/
https://www.ncbi.nlm.nih.gov/pubmed/20299467
http://dx.doi.org/10.2337/db09-1295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874704/
https://www.ncbi.nlm.nih.gov/pubmed/20299467
http://dx.doi.org/10.2337/db09-1295

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