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Platelet Tissue Factor Synthesis in Type 2 Diabetic Patients Is Resistant to Inhibition by Insulin

OBJECTIVE: Patients with type 2 diabetes have an increased risk of cardiovascular disease and show abnormalities in the coagulation cascade. We investigated whether increased synthesis of tissue factor (TF) by platelets could contribute to the hypercoagulant state. RESEARCH DESIGN AND METHODS: Plate...

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Detalles Bibliográficos
Autores principales: Gerrits, Anja J., Koekman, Cornelis A., van Haeften, Timon W., Akkerman, Jan Willem N.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874710/
https://www.ncbi.nlm.nih.gov/pubmed/20200314
http://dx.doi.org/10.2337/db09-1008