High-Mobility Group Box-1 Protein Promotes Angiogenesis After Peripheral Ischemia in Diabetic Mice Through a VEGF-Dependent Mechanism

OBJECTIVE: High-mobility group box-1 (HMGB1) protein is a nuclear DNA-binding protein released from necrotic cells, inducing inflammatory responses and promoting tissue repair and angiogenesis. Diabetic human and mouse tissues contain lower levels of HMGB1 than their normoglycemic counterparts. Defi...

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Detalles Bibliográficos
Autores principales: Biscetti, Federico, Straface, Giuseppe, De Cristofaro, Raimondo, Lancellotti, Stefano, Rizzo, Paola, Arena, Vincenzo, Stigliano, Egidio, Pecorini, Giovanni, Egashira, Kensuke, De Angelis, Giulia, Ghirlanda, Giovanni, Flex, Andrea
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874711/
https://www.ncbi.nlm.nih.gov/pubmed/20200317
http://dx.doi.org/10.2337/db09-1507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874711/
https://www.ncbi.nlm.nih.gov/pubmed/20200317
http://dx.doi.org/10.2337/db09-1507

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