Cardiac-Specific IGF-1 Receptor Transgenic Expression Protects Against Cardiac Fibrosis and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy

OBJECTIVE: Compelling epidemiological and clinical evidence has identified a specific cardiomyopathy in diabetes, characterized by early diastolic dysfunction and adverse structural remodeling. Activation of the insulin-like growth factor 1 (IGF-1) receptor (IGF-1R) promotes physiological cardiac gr...

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Detalles Bibliográficos
Autores principales: Huynh, Karina, McMullen, Julie R., Julius, Tracey L., Tan, Joon Win, Love, Jane E., Cemerlang, Nelly, Kiriazis, Helen, Du, Xiao-Jun, Ritchie, Rebecca H.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874713/
https://www.ncbi.nlm.nih.gov/pubmed/20215428
http://dx.doi.org/10.2337/db09-1456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874713/
https://www.ncbi.nlm.nih.gov/pubmed/20215428
http://dx.doi.org/10.2337/db09-1456

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