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Identification of genetic modifiers of behavioral phenotypes in serotonin transporter knockout rats

BACKGROUND: Genetic variation in the regulatory region of the human serotonin transporter gene (SLC6A4) has been shown to affect brain functionality and personality. However, large heterogeneity in its biological effects is observed, which is at least partially due to genetic modifiers. To gain insi...

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Detalles Bibliográficos
Autores principales: Homberg, Judith, Nijman, Isaäc J, Kuijpers, Sylvia, Cuppen, Edwin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874760/
https://www.ncbi.nlm.nih.gov/pubmed/20459657
http://dx.doi.org/10.1186/1471-2156-11-37