Cargando…

Identification of genetic modifiers of behavioral phenotypes in serotonin transporter knockout rats

BACKGROUND: Genetic variation in the regulatory region of the human serotonin transporter gene (SLC6A4) has been shown to affect brain functionality and personality. However, large heterogeneity in its biological effects is observed, which is at least partially due to genetic modifiers. To gain insi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Homberg, Judith, Nijman, Isaäc J, Kuijpers, Sylvia, Cuppen, Edwin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874760/ https://www.ncbi.nlm.nih.gov/pubmed/20459657 http://dx.doi.org/10.1186/1471-2156-11-37

Ejemplares similares

Knockout serotonin transporter in rats moderates outcome and stimulus generalization
por: Guo, Chao Ciu-Gwok, et al.
Publicado: (2021)

Correction: Knockout serotonin transporter in rats moderates outcome and stimulus generalization
por: Guo, Chao Ciu-Gwok, et al.
Publicado: (2022)

Functional and Structural Neural Network Characterization of Serotonin Transporter Knockout Rats
por: van der Marel, Kajo, et al.
Publicado: (2013)

Enrichment Environment Positively Influences Depression- and Anxiety-Like Behavior in Serotonin Transporter Knockout Rats through the Modulation of Neuroplasticity, Spine, and GABAergic Markers
por: Sbrini, Giulia, et al.
Publicado: (2020)

Impaired fear extinction in serotonin transporter knockout rats is associated with increased 5‐hydroxymethylcytosine in the amygdala
por: Shan, Ling, et al.
Publicado: (2018)

BDNF Overexpression in the Ventral Hippocampus Promotes Antidepressant- and Anxiolytic-Like Activity in Serotonin Transporter Knockout Rats
por: Diniz, Danielle M., et al.
Publicado: (2021)

Impaired Fear Extinction as Displayed by Serotonin Transporter Knockout Rats Housed in Open Cages Is Disrupted by IVC Cage Housing
por: Shan, Ling, et al.
Publicado: (2014)

Hypersensitivity to amphetamine's psychomotor and reinforcing effects in serotonin transporter knockout rats: Glutamate in the nucleus accumbens
por: Caffino, Lucia, et al.
Publicado: (2020)

Alterations of mitochondrial dynamics in serotonin transporter knockout rats: A possible role in the fear extinction recall mechanisms
por: Brivio, Paola, et al.
Publicado: (2022)

Long access to cocaine self‐administration dysregulates the glutamate synapse in the nucleus accumbens core of serotonin transporter knockout rats
por: Caffino, Lucia, et al.
Publicado: (2021)

Responsivity of serotonin transporter knockout rats to short and long access to cocaine: Modulation of the glutamate signalling in the nucleus accumbens shell
por: Caffino, Lucia, et al.
Publicado: (2022)

Impaired Fear Extinction Recall in Serotonin Transporter Knockout Rats Is Transiently Alleviated during Adolescence
por: Schipper, Pieter, et al.
Publicado: (2019)

Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice
por: Shoji, Hirotaka, et al.
Publicado: (2023)

Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats
por: Homberg, Judith R., et al.
Publicado: (2007)

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals
por: van Boxtel, Ruben, et al.
Publicado: (2008)

Ultrahigh‐resolution MRI reveals structural brain differences in serotonin transporter knockout rats after sucrose and cocaine self‐administration
por: Karel, Peter, et al.
Publicado: (2019)

Altered inflammatory responsiveness in serotonin transporter mutant rats
por: Macchi, Flavia, et al.
Publicado: (2013)

Tramadol’s Inhibitory Effects on Sexual Behavior: Pharmacological Studies in Serotonin Transporter Knockout Rats
por: Esquivel-Franco, Diana C., et al.
Publicado: (2018)

A genome-wide SNP panel for mapping and association studies in the rat
por: Nijman, Isaäc J, et al.
Publicado: (2008)

Serotonin transporter deficiency alters socioemotional ultrasonic communication in rats
por: Golebiowska, Joanna, et al.
Publicado: (2019)

Neonatal Tactile Stimulation Alters Behaviors in Heterozygous Serotonin Transporter Male Rats: Role of the Amygdala
por: Roversi, Karine, et al.
Publicado: (2020)

Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach
por: Mokry, Michal, et al.
Publicado: (2011)

Bacterial Lipopolysaccharide Increases Serotonin Metabolism in Both Medial Prefrontal Cortex and Nucleus Accumbens in Male Wild Type Rats, but Not in Serotonin Transporter Knockout Rats
por: Korte-Bouws, Gerdien A. H., et al.
Publicado: (2018)

Fear Extinction and Predictive Trait-Like Inter-Individual Differences in Rats Lacking the Serotonin Transporter
por: Willadsen, Maria, et al.
Publicado: (2021)

Threat-Avoidance Tendencies Moderate the Link Between Serotonin Transporter Genetic Variation and Reactive Aggression
por: Peeters, Deborah G. A., et al.
Publicado: (2020)

Behavioral lateralization of mice varying in serotonin transporter genotype
por: Stieger, Binia, et al.
Publicado: (2023)

Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia
por: Cinque, Stefano, et al.
Publicado: (2018)

Pharmacological Studies on the Role of 5-HT(1)(A) Receptors in Male Sexual Behavior of Wildtype and Serotonin Transporter Knockout Rats
por: Esquivel-Franco, Diana Carolina, et al.
Publicado: (2020)

Peripheral Serotonin Deficiency Affects Anxiety-like Behavior and the Molecular Response to an Acute Challenge in Rats
por: Sbrini, Giulia, et al.
Publicado: (2022)

Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice
por: Kerr, Travis M, et al.
Publicado: (2013)

Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice
por: Line, Samantha J., et al.
Publicado: (2011)

Potentiated serotonin signaling in serotonin re‐uptake transporter knockout mice increases enterocyte mass and small intestinal absorptive function
por: Greig, Chasen J., et al.
Publicado: (2019)

Editorial perspective of the Research Topic “Deciphering serotonin's role in neurodevelopment”
por: Homberg, Judith R., et al.
Publicado: (2013)

Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression
por: Spinelli, Simona, et al.
Publicado: (2013)

PM334. Effects of chronic tryptophan depletion on autism spectrum disorder like behaviors in serotonin transporter knockout and heterozygous mice
por: Tanaka, Miho, et al.
Publicado: (2016)

The association between serotonin transporter availability and the neural correlates of fear bradycardia
por: Schipper, Pieter, et al.
Publicado: (2019)

Serotonin/Dopamine Interactions in a Hyperactive Mouse: Reduced Serotonin Receptor 1B Activity Reverses Effects of Dopamine Transporter Knockout
por: Hall, Frank Scott, et al.
Publicado: (2014)

The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short‐ and long‐access cocaine self‐administration
por: Caffino, Lucia, et al.
Publicado: (2020)

Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice
por: Kasahara, Yoshiyuki, et al.
Publicado: (2019)

Dopamine Transporter Knockout Rats Show Impaired Wellbeing in a Multimodal Severity Assessment Approach
por: Mallien, Anne Stephanie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pd5o9bak5pqmc4317bt2m5pl94