Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans

BACKGROUND: The C. elegans gene folt-1 is an ortholog of the human reduced folate carrier gene. The FOLT-1 protein has been shown to transport folate and to be involved in uptake of exogenous folate by worms. A knockout mutation of the gene, folt-1(ok1460), was shown to cause sterility, and here we...

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Detalles Bibliográficos
Autores principales: Austin, Misa U, Liau, Wei-Siang, Balamurugan, Krishnaswamy, Ashokkumar, Balasubramaniem, Said, Hamid M, LaMunyon, Craig W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874772/
https://www.ncbi.nlm.nih.gov/pubmed/20441590
http://dx.doi.org/10.1186/1471-213X-10-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874772/
https://www.ncbi.nlm.nih.gov/pubmed/20441590
http://dx.doi.org/10.1186/1471-213X-10-46

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