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Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans
BACKGROUND: The C. elegans gene folt-1 is an ortholog of the human reduced folate carrier gene. The FOLT-1 protein has been shown to transport folate and to be involved in uptake of exogenous folate by worms. A knockout mutation of the gene, folt-1(ok1460), was shown to cause sterility, and here we...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874772/ https://www.ncbi.nlm.nih.gov/pubmed/20441590 http://dx.doi.org/10.1186/1471-213X-10-46 |