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Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse

BACKGROUND: Transglutaminase 2 (TG2), a cross-linking enzyme that confers supra-molecular structures with extra rigidity and resistance against proteolytic degradation, is expressed in the shoulder regions of human atherosclerotic plaques. It has been proposed that TG2 prevents tearing and promotes...

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Detalles Bibliográficos
Autores principales: Williams, Helen, Pease, Richard J., Newell, Laura M., Cordell, Paul A., Graham, Robert M., Kearney, Mark T., Jackson, Christopher L., Grant, Peter J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874840/
https://www.ncbi.nlm.nih.gov/pubmed/20003977
http://dx.doi.org/10.1016/j.atherosclerosis.2009.11.014