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Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse
BACKGROUND: Transglutaminase 2 (TG2), a cross-linking enzyme that confers supra-molecular structures with extra rigidity and resistance against proteolytic degradation, is expressed in the shoulder regions of human atherosclerotic plaques. It has been proposed that TG2 prevents tearing and promotes...
Autores principales: | Williams, Helen, Pease, Richard J., Newell, Laura M., Cordell, Paul A., Graham, Robert M., Kearney, Mark T., Jackson, Christopher L., Grant, Peter J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874840/ https://www.ncbi.nlm.nih.gov/pubmed/20003977 http://dx.doi.org/10.1016/j.atherosclerosis.2009.11.014 |
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