An Unusual Carbon-Carbon Bond Cleavage Reaction During Phosphinothricin Biosynthesis

Natural products containing phosphorus-carbon bonds have found widespread use in medicine and agriculture1. One such compound, phosphinothricin tripeptide (PTT), contains the unusual amino acid phosphinothricin (PT) attached to two alanine residues (Fig. 1). Synthetic PT (glufosinate) is a component...

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Detalles Bibliográficos
Autores principales: Cicchillo, Robert M., Zhang, Houjin, Blodgett, Joshua A.V., Whitteck, John T., Li, Gongyong, Nair, Satish K., van der Donk, Wilfred A., Metcalf, William W.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874955/
https://www.ncbi.nlm.nih.gov/pubmed/19516340
http://dx.doi.org/10.1038/nature07972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874955/
https://www.ncbi.nlm.nih.gov/pubmed/19516340
http://dx.doi.org/10.1038/nature07972

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