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Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Proteins

Although Duchenne muscular dystrophy is primarily classified as a neuromuscular disease, cardiac complications play an important role in the course of this X-linked inherited disorder. The pathobiochemical steps causing a progressive decline in the dystrophic heart are not well understood. We theref...

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Detalles Bibliográficos
Autores principales: Lewis, Caroline, Jockusch, Harald, Ohlendieck, Kay
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874991/
https://www.ncbi.nlm.nih.gov/pubmed/20508850
http://dx.doi.org/10.1155/2010/648501