Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions

How DNA repair machineries detect and access, within the context of chromatin, lesions inducing little or no distortion of the DNA structure is a poorly understood process. Removal of oxidized bases is initiated by a DNA glycosylase that recognises and excises the damaged base, initiating the base e...

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Detalles Bibliográficos
Autores principales: Amouroux, Rachel, Campalans, Anna, Epe, Bernd, Radicella, J. Pablo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875005/
https://www.ncbi.nlm.nih.gov/pubmed/20071746
http://dx.doi.org/10.1093/nar/gkp1247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875005/
https://www.ncbi.nlm.nih.gov/pubmed/20071746
http://dx.doi.org/10.1093/nar/gkp1247

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