Aromatic N versus aromatic F: bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs

The thermodynamics of base pairing is of fundamental importance. Fluorinated base analogs are valuable tools for investigating pairing interactions. To understand the influence of direct base–base interactions in relation to the role of water, pairing free energies between natural nucleobases and fl...

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Detalles Bibliográficos
Autores principales: Koller, Alrun N., Božilović, Jelena, Engels, Joachim W., Gohlke, Holger
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875010/
https://www.ncbi.nlm.nih.gov/pubmed/20081201
http://dx.doi.org/10.1093/nar/gkp1237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875010/
https://www.ncbi.nlm.nih.gov/pubmed/20081201
http://dx.doi.org/10.1093/nar/gkp1237

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