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Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin

DNA-damaging agents cause a multifaceted cellular stress response. Cells set in motion either repair mechanisms or programmed cell death pathways, depending on the extent of the damage and on their ability to withstand it. The RNA-binding protein (RBP) Sam68, which is up-regulated in prostate carcin...

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Detalles Bibliográficos
Autores principales: Busà, Roberta, Geremia, Raffaele, Sette, Claudio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875014/
https://www.ncbi.nlm.nih.gov/pubmed/20110258
http://dx.doi.org/10.1093/nar/gkq004