Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA

Aminoglycosides antibiotics negate dissociation and recycling of the bacterial ribosome’s subunits by binding to Helix 69 (H69) of 23S rRNA. The differential binding of various aminoglycosides to the chemically synthesized terminal domains of the Escherichia coli and human H69 has been characterized...

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Detalles Bibliográficos
Autores principales: Scheunemann, Ann E., Graham, William D., Vendeix, Franck A. P., Agris, Paul F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875026/
https://www.ncbi.nlm.nih.gov/pubmed/20110260
http://dx.doi.org/10.1093/nar/gkp1253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875026/
https://www.ncbi.nlm.nih.gov/pubmed/20110260
http://dx.doi.org/10.1093/nar/gkp1253

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