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Translation efficiency in humans: tissue specificity, global optimization and differences between developmental stages
Various studies in unicellular and multicellular organisms have shown that codon bias plays a significant role in translation efficiency (TE) by co-adaptation to the tRNA pool. Yet, in humans and other mammals the role of codon bias is still an open question, with contradictory results from differen...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875035/ https://www.ncbi.nlm.nih.gov/pubmed/20097653 http://dx.doi.org/10.1093/nar/gkq009 |