Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours

Hypoxia contributes to the aggressive and treatment-resistant phenotype of pancreatic ductal adenocarcinoma (PDAC). Oncolytic vaccinia virus has potential as an anti-tumour agent but the ability to lyse hypoxic tumour cells is vital for clinical efficacy. We hypothesised that unique aspects of the p...

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Detalles Bibliográficos
Autores principales: Hiley, Crispin T, Yuang, Ming, Lemoine, Nick R, Wang, Yaohe
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875103/
https://www.ncbi.nlm.nih.gov/pubmed/19890355
http://dx.doi.org/10.1038/gt.2009.132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875103/
https://www.ncbi.nlm.nih.gov/pubmed/19890355
http://dx.doi.org/10.1038/gt.2009.132

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