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Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

BACKGROUND: The zinc-finger transcription factor GLI3 is an important mediator of Sonic hedgehog signaling and crucial for patterning of many aspects of the vertebrate body plan. In vertebrates, the mechanism of SHH signal transduction and its action on target genes by means of activating or repress...

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Detalles Bibliográficos
Autores principales: Abbasi, Amir A, Paparidis, Zissis, Malik, Sajid, Bangs, Fiona, Schmidt, Ansgar, Koch, Sabine, Lopez-Rios, Javier, Grzeschik, Karl-Heinz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875213/
https://www.ncbi.nlm.nih.gov/pubmed/20426846
http://dx.doi.org/10.1186/1471-213X-10-44