Decreasing expression of the G(1)-phase inhibitors, p21Cip1 and p16INK4a, promotes division of corneal endothelial cells from older donors

PURPOSE: The current studies were conducted to determine whether the cyclin-dependent kinase inhibitors, p21Cip1 (p21 cyclin-dependent kinase-interacting protein 1) and p16INK4a (p16 cyclin-dependent kinase inhibitor 1A), help mediate G(1)-phase inhibition in human corneal endothelial cells (HCEC) b...

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Detalles Bibliográficos
Autores principales: Joyce, Nancy C., Harris, Deshea L.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875254/
https://www.ncbi.nlm.nih.gov/pubmed/20508865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875254/
https://www.ncbi.nlm.nih.gov/pubmed/20508865

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