Active Chromatin Marks Are Retained on X Chromosomes Lacking Gene or Repeat Silencing Despite XIST/Xist Expression in Somatic Cell Hybrids

BACKGROUND: X-chromosome inactivation occurs early in mammalian development and results in the inactive X chromosome acquiring numerous hallmarks of heterochromatin. While XIST is a key player in the inactivation process, the method of action of this ncRNA is yet to be determined. METHODOLOGY/PRINCI...

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Detalles Bibliográficos
Autores principales: Thorogood, Nancy P., Brown, Carolyn J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875404/
https://www.ncbi.nlm.nih.gov/pubmed/20520737
http://dx.doi.org/10.1371/journal.pone.0010787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875404/
https://www.ncbi.nlm.nih.gov/pubmed/20520737
http://dx.doi.org/10.1371/journal.pone.0010787

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