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Renin-angiotensin system activation correlates with microvascular dysfunction in a prospective cohort study of clinical sepsis

INTRODUCTION: Microvascular dysregulation characterized by hyporesponsive vessels and heterogeneous bloodflow is implicated in the pathogenesis of organ failure in sepsis. The renin-angiotensin system (RAS) affects the microvasculature, yet the relationships between RAS and organ injury in clinical...

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Detalles Bibliográficos
Autores principales: Doerschug, Kevin C, Delsing, Angela S, Schmidt, Gregory A, Ashare, Alix
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875539/
https://www.ncbi.nlm.nih.gov/pubmed/20175923
http://dx.doi.org/10.1186/cc8887