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A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis
Transforming growth factor beta (TGFβ) is a growth factor with many faces. In our osteoarthritis (OA) research we have found that TGFβ can be protective as well as deleterious for articular cartilage. We postulate that the dual effects of TGFβ on chondrocytes can be explained by the fact that TGFβ c...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875624/ https://www.ncbi.nlm.nih.gov/pubmed/20156325 http://dx.doi.org/10.1186/ar2896 |