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A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

Transforming growth factor beta (TGFβ) is a growth factor with many faces. In our osteoarthritis (OA) research we have found that TGFβ can be protective as well as deleterious for articular cartilage. We postulate that the dual effects of TGFβ on chondrocytes can be explained by the fact that TGFβ c...

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Detalles Bibliográficos
Autores principales:	van der Kraan, Peter M, Blaney Davidson, Esmeralda N, van den Berg, Wim B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875624/ https://www.ncbi.nlm.nih.gov/pubmed/20156325 http://dx.doi.org/10.1186/ar2896

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