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Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc

INTRODUCTION: Intervertebral disc (IVD) degeneration is considered a major underlying factor in the pathogenesis of chronic low back pain. Although the healthy IVD is both avascular and aneural, during degeneration there is ingrowth of nociceptive nerve fibres and blood vessels into proximal regions...

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Detalles Bibliográficos
Autores principales: Tolofari, Sotonye K, Richardson, Stephen M, Freemont, Anthony J, Hoyland, Judith A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875625/
https://www.ncbi.nlm.nih.gov/pubmed/20051117
http://dx.doi.org/10.1186/ar2898