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Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment

INTRODUCTION: Cross-regulation between TNF and type I IFN has been postulated to play an important role in autoimmune diseases. Therefore, we determined the effect of TNF blockade in rheumatoid arthritis (RA) on the type I IFN response gene activity in relation to clinical response. METHODS: Periphe...

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Detalles Bibliográficos
Autores principales: van Baarsen, Lisa GM, Wijbrandts, Carla A, Rustenburg, François, Cantaert, Tineke, van der Pouw Kraan, Tineke CTM, Baeten, Dominique L, Dijkmans, Ben AC, Tak, Paul P, Verweij, Cornelis L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875639/
https://www.ncbi.nlm.nih.gov/pubmed/20096109
http://dx.doi.org/10.1186/ar2912