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RNAi-mediated CD40-CD154 interruption promotes tolerance in autoimmune arthritis

INTRODUCTION: We have previously demonstrated that ex vivo inhibition of costimulatory molecules on antigen-pulsed dendritic cells (DCs) can be useful for induction of antigen-specific immune deviation and suppression of autoimmune arthritis in the collagen induced arthritis (CIA) model. The current...

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Detalles Bibliográficos
Autores principales: Zheng, Xiufen, Suzuki, Motohiko, Zhang, Xusheng, Ichim, Thomas E, Zhu, Fei, Ling, Hong, Shunnar, Aminah, Wang, Michael H, Garcia, Bertha, Inman, Robert D, Min, Wei-Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875641/
https://www.ncbi.nlm.nih.gov/pubmed/20102615
http://dx.doi.org/10.1186/ar2914