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Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress

INTRODUCTION: Synovial fibroblasts from rheumatoid arthritis show resistance to apoptotic stimuli, indicating they may be difficult to treat. To clearly understand these mechanisms of resistance, rheumatoid and osteoarthritis synovial fibroblasts (RASF and OASF) were exposed to endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Shin, Yong-Joo, Han, Song-Hee, Kim, Do-Sung, Lee, Geum-Hwa, Yoo, Wan-Hee, Kang, Yong-Mo, Choi, Je-Yong, Lee, Yong Chul, Park, Seoung Ju, Jeong, Seul-Ki, Kim, Hyung-Tae, Chae, Soo-Wan, Jeong, Hyun-Ja, Kim, Hyung-Ryong, Chae, Han-Jung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875648/
https://www.ncbi.nlm.nih.gov/pubmed/20122151
http://dx.doi.org/10.1186/ar2921