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'Rac'-ing upstream to treat rheumatoid arthritis

Signal transduction pathways regulate the production and function of many cytokines implicated in immune-mediated diseases. Targeting these enzymes with small molecule inhibitors represents a fertile field for the treatment of rheumatoid arthritis. Recent successes with compounds that block upstream...

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Detalles Bibliográficos
Autor principal: Firestein, Gary S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875651/
https://www.ncbi.nlm.nih.gov/pubmed/20236447
http://dx.doi.org/10.1186/ar2924