The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis

The aetiology of anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis has not been well defined. Here we review two factors which may play a role in the pathogenesis of the disease: genetics and infection. In particular, we discuss the role of autoantibodies to LAMP-2, which ma...

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Detalles Bibliográficos
Autores principales: Willcocks, Lisa C, Lyons, Paul A, Rees, Andrew J, Smith, Kenneth GC
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875655/
https://www.ncbi.nlm.nih.gov/pubmed/20236493
http://dx.doi.org/10.1186/ar2928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875655/
https://www.ncbi.nlm.nih.gov/pubmed/20236493
http://dx.doi.org/10.1186/ar2928

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