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The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis
The aetiology of anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis has not been well defined. Here we review two factors which may play a role in the pathogenesis of the disease: genetics and infection. In particular, we discuss the role of autoantibodies to LAMP-2, which ma...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875655/ https://www.ncbi.nlm.nih.gov/pubmed/20236493 http://dx.doi.org/10.1186/ar2928 |