High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals

INTRODUCTION: To investigate whether monosodium urate (MSU) crystals induce the production of CCL2 (monocyte chemoattractant protein-1; MCP-1) in human fibroblast-like synoviocytes (FLS) and whether this mechanism would be affected by high-density lipoproteins (HDL). METHODS: Human FLS isolated from...

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Detalles Bibliográficos
Autores principales: Scanu, Anna, Oliviero, Francesca, Gruaz, Lyssia, Sfriso, Paolo, Pozzuoli, Assunta, Frezzato, Federica, Agostini, Carlo, Burger, Danielle, Punzi, Leonardo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875657/
https://www.ncbi.nlm.nih.gov/pubmed/20149224
http://dx.doi.org/10.1186/ar2930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875657/
https://www.ncbi.nlm.nih.gov/pubmed/20149224
http://dx.doi.org/10.1186/ar2930

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